Anesthetic Management for a Patient with Rosai-Dorfman Disease, Cowden Syndrome, and Lhermitte-Duclos Disease: An Extremely Rare Disease Combination

Rosai-Dorfman disease (RDD) is a rare condition that causes massive lymphadenopathy, most commonly in the cervical area. Cowden syndrome (CS) hamartomas skin and mucosa predisposes individuals to various malignancies. Lhermitte-Duclos (LDD), or dysplastic cerebellar gangliocytoma, often associated with CS. A 41-year-old female all three conditions presented abnormal uterine bleeding endometrial intraepithelial neoplasia (EIN). Precautions should be considered when evaluating patients RDD CS preoperatively during airway management owing potential for multisystem involvement, anatomical distortion, difficult airways. The likelihood of having extremely rare.